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Ovarian cancer

Maternal health research

Below is a selection of studies exploring the impact of breastfeeding on ovarian cancer risk. For more details on this, see our maternal health meta-analyses research section.

Breastfeeding factors and risk of epithelial ovarian cancer

This US study examined the association between breastfeeding factors and epithelial ovarian cancer (EOC). It found that compared to never breastfeeding, breastfeeding any offspring was associated with a 30% reduction in EOC risk. That association lasted more than 30 years and was dose-respondent, and an earlier age at first breastfeeding was further associated with increased protection.

Modugno, F, Goughnour, S, Wallack, D, et al, (2019). Breastfeeding factors and risk of epithelial ovarian cancer. Gynecologic Oncology 2019 January 25

The fraction of cancer attributable to modifiable risk factors in England, Wales, Scotland, Northern Ireland, and the United Kingdom in 2015

This study explored the fraction of cancer cases attributable to modifiable risk factors in the UK, finding that nearly four in ten (37.7%) cancer cases in 2015 in the UK were attributable to known risk factors. Researchers identified not breastfeeding as one such risk factor; amongst women, not breastfeeding was attributed to 2,582 cancer cases in 2015.

Brown, K, et al, (2018). The fraction of cancer attributable to modifiable risk factors in England, Wales, Scotland, Northern Ireland, and the United Kingdom in 2015, British Journal of Cancer, doi:10.1038/s41416-018-0029-6.

Older research 

  • The Effect of Breastfeeding Duration and Parity on the Risk of Epithelial Ovarian Cancer: A Systematic Review and Meta-analysis

Sung, HK, et al (2016). The Effect of Breastfeeding Duration and Parity on the Risk of Epithelial Ovarian Cancer: A Systematic Review and Meta-analysis, Journal of Preventative Medicine and Public Health, DOI: 10.3961/jpmph.16.066

  • Breastfeeding and ovarian cancer risk: a systematic review and meta-analysis of 40 epidemiological studies

Li, DP, et al (2014). Breastfeeding and ovarian cancer risk: a systematic review and meta-analysis of 40 epidemiological studies, Asian Pacific Journal of Cancer Prevention, PMID: 24998548

  • Breastfeeding and ovarian cancer risk: a meta-analysis of epidemiologic studies

Luan, NN, et al (2013). Breastfeeding and ovarian cancer risk: a meta-analysis of epidemiologic studies, The American Journal of Clinical Nutrition, DOI: 10.3945/ajcn.113.062794

 

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Maternal Health Meta Analyses and Other

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